The p53 Pathway and Metabolism: The Tree That Hides the Forest

The p53 Pathway and Metabolism: The Tree That Hides the Forest

The p53 pathway is functionally inactivated in most, if not all, human cancers. The p53 protein is a central effector of numerous stress-related molecular cascades. p53 controls a safeguard mechanism that prevents accumulation of abnormal cells and their transformation by regulating DNA repair, cell...

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Bibliographic Details
Main Authors: Airelle Lahalle, Matthieu Lacroix, Carlo De Blasio, Madi Y. Cissé, Laetitia K. Linares, Laurent Le Cam
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
p53 pathway
metabolism
network
cancer
aging
metabolic disease
Online Access:https://www.mdpi.com/2072-6694/13/1/133

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