TNF-alpha and insulin-resistance: metabolic effects of in vivo therapeutic blockade

TNF-alpha and insulin-resistance: metabolic effects of in vivo therapeutic blockade

Insulin resistance is a key pathophysiologic feature of obesity, type 2 diabetes mellitus and prediabetic states (impaired fasting glucose, impaired glucose tolerance). TNF-α, a proinflammatory cytokine, plays an important role in the pathogenesis of insulin resistance associated with inflammation d...

Full description

Bibliographic Details
Main Author:	F. Ursini
Format:	Article
Language:	English
Published:	PAGEPress Publications 2011-06-01
Series:	Reumatismo
Online Access:	http://www.reumatismo.org/index.php/reuma/article/view/449

Similar Items

New Insights on the Effect of TNF Alpha Blockade by Gene Silencing in Noise-Induced Hearing Loss
by: Janaína C. Rodrigues, et al.
Published: (2020-04-01)

Are there any positive effects of TNF-alpha blockers on bone metabolism?
by: A. Sulli, et al.
Published: (2011-09-01)

In Vivo Evaluation of TNF-Alpha in the Lungs of Patients Affected by Sarcoidosis
by: Filippo Galli, et al.
Published: (2015-01-01)

TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma
by: Florie Bertrand, et al.
Published: (2017-12-01)

In vivo therapeutic efficacy of TNFα silencing by folate-PEG-chitosan-DEAE/siRNA nanoparticles in arthritic mice
by: Shi Q, et al.
Published: (2018-01-01)

Lymphocutaneous Sporotrichosis during Treatment with Anti-TNF-Alpha Monotherapy
by: Francesco Ursini, et al.
Published: (2015-01-01)

Correlation of Neopterin and TNF-alpha with Asymmetric Dimethylarginine in Metabolic Syndrome
by: Dedeh Yuniarty, et al.
Published: (2011-12-01)

TNF-α Downregulation Modifies Insulin Receptor Substrate 1 (IRS-1) in Metabolic Signaling of Diabetic Insulin-Resistant Hepatocytes
by: Iraj Alipourfard, et al.
Published: (2019-01-01)

The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics
by: Dan-in Jang, et al.
Published: (2021-03-01)

Effect of TNF-Alpha on Caveolin-1 Expression and Insulin Signaling During Adipocyte Differentiation and in Mature Adipocytes
by: Sara Palacios-Ortega, et al.
Published: (2015-07-01)

Tnf(alpha)-dependent and Tnf(alpha)-independent Activation of Macrophage Effector Function
by: Clemons-miller, Annette R.
Published: (1998)

Insulin resistance in therapeutic clinic
by: Anna V. Pashentseva, et al.
Published: (2017-09-01)

TNF-[alpha] in host immunity to tuberculosis : in vivo and in vitro studies of protection and pathogenesis
by: Bekker, Linda-Gail
Published: (2014)

Hip arthritis in the TNF-Blockade era: an unresolved issue?
by: Scott C, et al.
Published: (2008-09-01)

Non-invasive detection of divergent metabolic signals in insulin deficiency vs. insulin resistance in vivo
by: Cornelius von Morze, et al.
Published: (2018-02-01)

Vascular Damage in Resistant Hypertension: TNF-Alpha Inhibition Effects on Endothelial Cells
by: Natália Ruggeri Barbaro, et al.
Published: (2015-01-01)

In Vivo Interrelationship between Insulin Resistance and Interferon Gamma Production: Protective and Therapeutic Effect of Berberine
by: Mohammad Ahmad Mahmoud, et al.
Published: (2016-01-01)

Therapeutic Strategies for the Treatment of Insulin Resistance in Various Metabolic Disease States
by: Asp, Michelle Lynn
Published: (2010)

The role of the peroxisome-proliferator-activated receptor alpha in modulating glucose intolerance and insulin action using in vivo models of insulin resistance
by: Smith, Nicholas Derek
Published: (2006)

Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation
by: Katy Diallo, et al.
Published: (2021-04-01)

Identification of the Schistosoma mansoni TNF-alpha receptor gene and the effect of human TNF-alpha on the parasite gene expression profile.
by: Katia C Oliveira, et al.
Published: (2009-01-01)

TNF-α Autocrine Feedback Loops in Human Monocytes: The Pro- and Anti-Inflammatory Roles of the TNF-α Receptors Support the Concept of Selective TNFR1 Blockade In Vivo
by: Jennie M. Gane, et al.
Published: (2016-01-01)

G308A polymorphism of TNF-alpha gene is associated with insulin resistance and histological changes in non alcoholic fatty liver disease patients
by: Rocio Alter, et al.
Published: (2010-10-01)

PGBR extract ameliorates TNF-α induced insulin resistance in hepatocytes
by: Fu-Chih Chen, et al.
Published: (2018-01-01)

TNF-α involvement in insulin resistance induced by experimental scorpion envenomation.
by: Aouatef Ait-Lounis, et al.
Published: (2012-01-01)

Effects of TNF-alpha inhibition on inner ear microcirculation and hearing function after acute loud noise in vivo
by: Arpornchayanon, Warangkana
Published: (2010)

Therapeutic Potential of TNFα and IL1β Blockade for CRS/ICANS in CAR-T Therapy via Ameliorating Endothelial Activation
by: Yunshuo Chen, et al.
Published: (2021-05-01)

Weight loss and metabolic alterations induced by recombinant tumour necrosis FACTOR-ALPHA (TNF)
by: Mahony, Susan M.
Published: (1989)

Skimmin Improves Insulin Resistance via Regulating the Metabolism of Glucose: In Vitro and In Vivo Models
by: Guoqiang Zhang, et al.
Published: (2020-04-01)

Zinc transporters and insulin resistance: therapeutic implications for type 2 diabetes and metabolic disease
by: Shaghayegh Norouzi, et al.
Published: (2017-11-01)

Anti-TNF-alpha-induced lupus
by: Michel De Bandt
Published: (2019-11-01)

The Additive Inflammatory In Vivo and In Vitro Effects of IL-7 and TSLP in Arthritis Underscore the Therapeutic Rationale for Dual Blockade.
by: Maarten R Hillen, et al.
Published: (2015-01-01)

Effect of ursolic acid on TNFα-induced insulin resistance through regulating mitochondrial dynamics
by: Nurmaamaamaa Chadraabal, et al.
Published: (2018)

AT1 receptor blockade attenuates insulin resistance and myocardial remodeling in rats with diet-induced obesity.
by: Silvio A Oliveira-Junior, et al.
Published: (2014-01-01)

Central nervous system effects of tumor necrosis factor alpha blockade
by: Schett Georg
Published: (2011-11-01)

Insulin resistance and lipid metabolism
by: Dimas Ikeoka, et al.
Published: (2009-01-01)

Insulin resistance and cardiac metabolism
by: Qi, Dake
Published: (2010)

Polymorphism of tumor necrosis factor alpha (TNF-alpha) gene promoter, circulating TNF-alpha level, and cardiovascular risk factor for ischemic stroke
by: Cui Guanglin, et al.
Published: (2012-10-01)

Effects of Resistance Training on Immunoinflammatory Response, TNF-Alpha Gene Expression, and Body Composition in Elderly Women
by: Luís Ângelo Macêdo Santiago, et al.
Published: (2018-01-01)

Effect of TNF-α Blockade in Gingival Crevicular Fluid on Periodontal Condition of Patients with Rheumatoid Arthritis
by: Zeinab Kadkhoda, et al.
Published: (2016-09-01)