An AMP-activated protein kinase complex with two distinctive alpha subunits is involved in nutritional stress responses in Trypanosoma cruzi.
Trypanosoma cruzi, the etiological agent of Chagas disease, has a digenetic life cycle. In its passage from the insect vector to the mammalian host, and vice versa, it must be prepared to cope with abrupt changes in environmental conditions, such as carbon source, pH, temperature and osmolarity, in...
Main Authors: | Tamara Sternlieb, Alejandra C Schoijet, Patricio D Genta, Salomé C Vilchez Larrea, Guillermo D Alonso |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-05-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://doi.org/10.1371/journal.pntd.0009435 |
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