An AMP-activated protein kinase complex with two distinctive alpha subunits is involved in nutritional stress responses in Trypanosoma cruzi.

Trypanosoma cruzi, the etiological agent of Chagas disease, has a digenetic life cycle. In its passage from the insect vector to the mammalian host, and vice versa, it must be prepared to cope with abrupt changes in environmental conditions, such as carbon source, pH, temperature and osmolarity, in...

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Bibliographic Details
Main Authors: Tamara Sternlieb, Alejandra C Schoijet, Patricio D Genta, Salomé C Vilchez Larrea, Guillermo D Alonso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009435