A randomized controlled trial comparing lithium plus valproic acid versus lithium plus carbamazepine in young patients with type 1 bipolar disorder: the LICAVAL study

Abstract Background Treatment of bipolar disorder (BD) usually requires drug combinations. Combinations of lithium plus valproic acid (Li/VPA) and lithium plus carbamazepine (Li/CBZ) are used in clinical practice but were not previously compared in a head-to-head trial. Objective The objective of th...

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Bibliographic Details
Main Authors: Giovani Missio, Doris Hupfeld Moreno, Frederico Navas Demetrio, Marcio Gerhardt Soeiro-de-Souza, Fernando dos Santos Fernandes, Vivian Boschesi Barros, Ricardo Alberto Moreno
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Trials
Online Access:http://link.springer.com/article/10.1186/s13063-019-3655-2