Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid Patient

Objectives: To highlight the occurrence of Hashimoto’s encephalopathy – a steroid-responsive encephalopathy associated with elevated antithyroid antibodies. Material and methods: We describe a clinically and biochemically euthyroid patient with an encephalopathy presenting with headache, mild confu...

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Main Authors:	Senthil Chandrasekaram, Emily Mudenha, Buddhike A Mendis, Antal Szabo, Devaka JS Fernando
Format:	Article
Language:	English
Published:	SMC MEDIA SRL 2014-10-01
Series:	European Journal of Case Reports in Internal Medicine
Subjects:	Autoimmune thyroid disease, encephalopathy, hashimotos disease
Online Access:	http://ejcrim.com/index.php/EJCRIM/article/view/141

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spelling	doaj-8ecca1a099ef4f72b10a5232667817d92020-11-24T22:55:09ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942014-10-011110.12890/2014_00014156Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid PatientSenthil Chandrasekaram0Emily Mudenha1Buddhike A Mendis2Antal Szabo3Devaka JS Fernando4Department of Endocrinology and Diabetes, King’s Mill Hospital, Sherwood Forest Hospital NHS Foundation Trust, Sutton-in-AshfieldDepartment of Endocrinology and Diabetes, King’s Mill Hospital, Sherwood Forest Hospital NHS Foundation Trust, Sutton-in-AshfieldDepartment of Endocrinology and Diabetes, King’s Mill Hospital, Sherwood Forest Hospital NHS Foundation Trust, Sutton-in-AshfieldDepartment of Endocrinology and Diabetes, King’s Mill Hospital, Sherwood Forest Hospital NHS Foundation Trust, Sutton-in-AshfieldDepartment of Endocrinology and Diabetes, King’s Mill Hospital, Sherwood Forest Hospital NHS Foundation Trust, Sutton-in-Ashfield Department of Diabetes and Endocrinology, University of Sheffield, Sheffield Postgraduate Medical Centre, Sheffield Hallam University, SheffieldObjectives: To highlight the occurrence of Hashimoto’s encephalopathy – a steroid-responsive encephalopathy associated with elevated antithyroid antibodies. Material and methods: We describe a clinically and biochemically euthyroid patient with an encephalopathy presenting with headache, mild confusion and personality changes for 6 weeks and tonic–clonic seizures upon admission Results: There was no obvious infective or metabolic cause. The patient had a high titre of antithyroid antibodies and responded to steroid therapy. Conclusion: This uncommon disease needs to be considered in patients presenting with neurological symptoms that remain unexplained after routine standard investigations, even when the patient is euthyroid. Early diagnosis is important, as this is a treatable condition.http://ejcrim.com/index.php/EJCRIM/article/view/141Autoimmune thyroid disease, encephalopathy, hashimotos disease
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Senthil Chandrasekaram Emily Mudenha Buddhike A Mendis Antal Szabo Devaka JS Fernando
spellingShingle	Senthil Chandrasekaram Emily Mudenha Buddhike A Mendis Antal Szabo Devaka JS Fernando Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid Patient European Journal of Case Reports in Internal Medicine Autoimmune thyroid disease, encephalopathy, hashimotos disease
author_facet	Senthil Chandrasekaram Emily Mudenha Buddhike A Mendis Antal Szabo Devaka JS Fernando
author_sort	Senthil Chandrasekaram
title	Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid Patient
title_short	Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid Patient
title_full	Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid Patient
title_fullStr	Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid Patient
title_full_unstemmed	Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid Patient
title_sort	hashimoto’s encephalopathy: an unusual cause of autoimmune encephalopathy in a clinically and biochemically euthyroid patient
publisher	SMC MEDIA SRL
series	European Journal of Case Reports in Internal Medicine
issn	2284-2594
publishDate	2014-10-01
description	Objectives: To highlight the occurrence of Hashimoto’s encephalopathy – a steroid-responsive encephalopathy associated with elevated antithyroid antibodies. Material and methods: We describe a clinically and biochemically euthyroid patient with an encephalopathy presenting with headache, mild confusion and personality changes for 6 weeks and tonic–clonic seizures upon admission Results: There was no obvious infective or metabolic cause. The patient had a high titre of antithyroid antibodies and responded to steroid therapy. Conclusion: This uncommon disease needs to be considered in patients presenting with neurological symptoms that remain unexplained after routine standard investigations, even when the patient is euthyroid. Early diagnosis is important, as this is a treatable condition.
topic	Autoimmune thyroid disease, encephalopathy, hashimotos disease
url	http://ejcrim.com/index.php/EJCRIM/article/view/141
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Hashimoto’s Encephalopathy: An Unusual Cause of Autoimmune Encephalopathy in a Clinically and Biochemically Euthyroid Patient

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