Bladder exstrophy: reconstructed female patients achieving normal pregnancy and delivering normal babies

• Main Authors: Amílcar Martins Giron, Carlo Camargo Passerotti, Hiep Nguyen, José Arnaldo Shiomi da Cruz, Miguel Srougi
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Urologia 2011-10-01
• Series: International Brazilian Journal of Urology
• Subjects: bladder exstrophy; outcomes; female; pregnancy
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382011000500006

PURPOSE: Bladder exstrophy (BE) is an anterior midline defect that causes a series of genitourinary and muscular malformations, which demands surgical intervention for correction. Women with BE are fertile and able to have children without this disease. The purpose of this study is to assess the sexual function and quality of life of women treated for BE. MATERIALS AND METHODS: All patients in our institution treated for BE from 1987 to 2007 were recruited to answer a questionnaire about their quality of life and pregnancies. RESULTS: Fourteen women were submitted to surgical treatment for BE and had 22 pregnancies during the studied period. From those, 17 pregnancies (77.2%) resulted in healthy babies, while four patients (18.1%) had a spontaneous abortion due to genital prolapse, and there was one case (4.7%) of death due to a pneumopathy one week after delivery. There was also one case (5.8%) of premature birth without greater repercussions. During pregnancy, three patients (21.4%) had urinary tract infections and one patient (7.14%) presented urinary retention. After delivery, three patients (21.4%) presented temporary urinary incontinence; one patient (7.14%) had a vesicocutaneous fistula and seven patients (50%) had genital prolapsed. All patients confirmed to have achieved urinary continence, a regular sexual life and normal pregnancies. All patients got married and pregnant older than the general population. CONCLUSIONS: BE is a severe condition that demands medical and family assistance. Nevertheless, it is possible for the bearers of this condition to have a satisfactory and productive lifestyle.