Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.

Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.

Five new diterpenoids 1–5 were isolated from an Okinawan soft coral, Cespitularia sp., together with the known diterpenoid, alcyonolide (6). New diterpenoid structures were elucidated by spectroscopic methods and by comparison of their NMR data with those of related compounds. Alcyonol...

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Bibliographic Details
Main Authors: Katsuhiro Ueda, Junsei Taira, Michael C. Roy, Wilmar Maarisit, Prodip K. Roy
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Marine Drugs
Subjects:
Cespitularia
cytotoxicity
diterpenoid
HCT 116 cells
alcyonolide
Online Access:http://www.mdpi.com/1660-3397/10/12/2741
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spelling doaj-8eca949e29d24ca193475408c457694c2020-11-25T01:24:10ZengMDPI AGMarine Drugs1660-33972012-11-0110122741274810.3390/md10122741Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.Katsuhiro UedaJunsei TairaMichael C. RoyWilmar MaarisitProdip K. RoyFive new diterpenoids 1–5 were isolated from an Okinawan soft coral, Cespitularia sp., together with the known diterpenoid, alcyonolide (6). New diterpenoid structures were elucidated by spectroscopic methods and by comparison of their NMR data with those of related compounds. Alcyonolide (6) was cytotoxic against HCT 116 cells (IC50 5.85 μM), while these new diterpenoids 1–5 were much less active (IC50 28.2–91.4 μM).http://www.mdpi.com/1660-3397/10/12/2741CespitulariacytotoxicityditerpenoidHCT 116 cellsalcyonolide
collection DOAJ
language English
format Article
sources DOAJ
author Katsuhiro Ueda
Junsei Taira
Michael C. Roy
Wilmar Maarisit
Prodip K. Roy
spellingShingle Katsuhiro Ueda
Junsei Taira
Michael C. Roy
Wilmar Maarisit
Prodip K. Roy
Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
Marine Drugs
Cespitularia
cytotoxicity
diterpenoid
HCT 116 cells
alcyonolide
author_facet Katsuhiro Ueda
Junsei Taira
Michael C. Roy
Wilmar Maarisit
Prodip K. Roy
author_sort Katsuhiro Ueda
title Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
title_short Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
title_full Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
title_fullStr Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
title_full_unstemmed Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
title_sort five new diterpenoids from an okinawan soft coral, cespitularia sp.
publisher MDPI AG
series Marine Drugs
issn 1660-3397
publishDate 2012-11-01
description Five new diterpenoids 1–5 were isolated from an Okinawan soft coral, Cespitularia sp., together with the known diterpenoid, alcyonolide (6). New diterpenoid structures were elucidated by spectroscopic methods and by comparison of their NMR data with those of related compounds. Alcyonolide (6) was cytotoxic against HCT 116 cells (IC50 5.85 μM), while these new diterpenoids 1–5 were much less active (IC50 28.2–91.4 μM).
topic Cespitularia
cytotoxicity
diterpenoid
HCT 116 cells
alcyonolide
url http://www.mdpi.com/1660-3397/10/12/2741
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AT wilmarmaarisit fivenewditerpenoidsfromanokinawansoftcoralcespitulariasp
AT prodipkroy fivenewditerpenoidsfromanokinawansoftcoralcespitulariasp
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