Co-administration of Pregabalin and Curcumin Synergistically Decreases Pain-Like Behaviors in Acute Nociceptive Pain Murine Models

Co-administration of Pregabalin and Curcumin Synergistically Decreases Pain-Like Behaviors in Acute Nociceptive Pain Murine Models

Analgesic drugs in a combination-form can achieve greater efficacy with lesser side effects compared to either drug alone. The combination of drugs acting at different targets or mechanisms of action has been recognized as an alternative approach for achieving optimal analgesia. In this study, the a...

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Bibliographic Details
Main Authors: Sarinee Leksiri, Hasriadi, Peththa Wadu Dasuni Wasana, Opa Vajragupta, Pornchai Rojsitthisak, Pasarapa Towiwat
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
pregabalin
curcumin
nociceptive pain
synergistic interaction
acetic acid-induced writhing test
tail-flick test
Online Access:https://www.mdpi.com/1420-3049/25/18/4172

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https://www.mdpi.com/1420-3049/25/18/4172

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