Isoprenaline/β2-AR activates Plexin-A1/VEGFR2 signals via VEGF secretion in gastric cancer cells to promote tumor angiogenesis

Isoprenaline/β2-AR activates Plexin-A1/VEGFR2 signals via VEGF secretion in gastric cancer cells to promote tumor angiogenesis

Abstract Background The role of stress signals in regulating gastric cancer initiation and progression is not quite clear. It is known that stress signals modulate multiple processes such as immune function, cell migration and angiogenesis. However, few studies have investigated the mechanisms of ho...

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Bibliographic Details
Main Authors: Yanjie Lu, Qian Xu, Yanzhen Zuo, Lei Liu, Shaochen Liu, Lei Chen, Kang Wang, Yuntao Lei, Xiangyang Zhao, Yuhong Li
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cancer
Subjects:
Gastric cancer
Angiogenesis
Isoprenaline
Plexin-A1
VEGFR2
Online Access:http://link.springer.com/article/10.1186/s12885-017-3894-0

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