Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer’s disease mice

Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer’s disease mice

Abstract Background A growing body of epidemiological literature indicates that particulate matter (PM) air pollution exposure is associated with elevated Alzheimer’s disease (AD) risk and may exacerbate AD-related cognitive decline. Of concern is exposure to the ultrafine PM (UFP) fraction (≤100 nm...

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Bibliographic Details
Main Authors: Katrina Jew, Denise Herr, Candace Wong, Andrea Kennell, Keith Morris-Schaffer, Günter Oberdörster, M. Kerry O’Banion, Deborah A. Cory-Slechta, Alison Elder
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Particle and Fibre Toxicology
Subjects:
Ultrafine particles
Air pollution
Learning
Memory
Neurodegeneration
Alzheimer’s disease
Online Access:http://link.springer.com/article/10.1186/s12989-019-0323-3

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