Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer’s disease mice

Abstract Background A growing body of epidemiological literature indicates that particulate matter (PM) air pollution exposure is associated with elevated Alzheimer’s disease (AD) risk and may exacerbate AD-related cognitive decline. Of concern is exposure to the ultrafine PM (UFP) fraction (≤100 nm...

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Bibliographic Details
Main Authors: Katrina Jew, Denise Herr, Candace Wong, Andrea Kennell, Keith Morris-Schaffer, Günter Oberdörster, M. Kerry O’Banion, Deborah A. Cory-Slechta, Alison Elder
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12989-019-0323-3