Association of mannose-binding lectin, ficolin-2 and immunoglobulin concentrations with future exacerbations in patients with chronic obstructive pulmonary disease: secondary analysis of the randomized controlled REDUCE trial

Association of mannose-binding lectin, ficolin-2 and immunoglobulin concentrations with future exacerbations in patients with chronic obstructive pulmonary disease: secondary analysis of the randomized controlled REDUCE trial

Abstract Background The innate and adaptive immune system is involved in the airway inflammation associated with acute exacerbations in patients with chronic obstructive pulmonary disease (COPD). We evaluated the association of mannose-binding lectin (MBL), immunoglobulin (Ig) and ficolin-2 concentr...

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Bibliographic Details
Main Authors: Severin Vogt, Jörg D. Leuppi, Philipp Schuetz, Beat Mueller, Carmen Volken, Sarah Dräger, Marten Trendelenburg, Jonas Rutishauser, Michael Osthoff
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Respiratory Research
Subjects:
Mannose-binding lectin
Ficolin-2
Immunoglobulin
Chronic obstructive pulmonary disease
Exacerbation
Glucocorticoid treatment
Online Access:https://doi.org/10.1186/s12931-021-01822-9

Internet

https://doi.org/10.1186/s12931-021-01822-9

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