OKlahoma Nitrone-007: novel treatment for diffuse intrinsic pontine glioma

OKlahoma Nitrone-007: novel treatment for diffuse intrinsic pontine glioma

Abstract Background Diffuse intrinsic pontine glioma (DIPG) is the most common brainstem cancer in childhood. This rapidly progressing brainstem glioma holds a very dismal prognosis with median survival of less than 1 year. Despite extensive research, no significant therapeutic advancements have bee...

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Bibliographic Details
Main Authors:	Lincy Thomas, Nataliya Smith, Debra Saunders, Michelle Zalles, Rafal Gulej, Megan Lerner, Kar-Ming Fung, Angel M. Carcaboso, Rheal A. Towner
Format:	Article
Language:	English
Published:	BMC 2020-11-01
Series:	Journal of Translational Medicine
Subjects:	Diffuse intrinsic pontine glioma (DIPG) ACVR1 mutation Patient-derived xenograft (PDX) OKN-007 Magnetic resonance imaging (MRI) Diffusion-weighted imaging (DWI)
Online Access:	http://link.springer.com/article/10.1186/s12967-020-02593-5

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