Methamphetamine-induced changes in myocardial gene transcription are sex-dependent

Methamphetamine-induced changes in myocardial gene transcription are sex-dependent

Abstract Background Prior work demonstrated that female rats (but not their male littermates) exposed to methamphetamine become hypersensitive to myocardial ischemic injury. Importantly, this sex-dependent effect persists following 30 days of subsequent abstinence from the drug, suggesting that it m...

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Bibliographic Details
Main Authors: Hasitha Chavva, Daniel A. Brazeau, James Denvir, Donald A. Primerano, Jun Fan, Sarah L. Seeley, Boyd R. Rorabaugh
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Genomics
Subjects:
Methamphetamine
Heart
Transcriptome
Sex differences
Circadian clock
Drug abuse
Online Access:https://doi.org/10.1186/s12864-021-07561-x

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