The effect of chemical and structural modifiers on the haemostatic process and cytotoxicity of the beta-chitin patch

Abstract Beta-chitin patch has previously been proven to be an effective haemostat, but whether modifying the patch affects its efficacy and safety, remains unanswered. In this study, the patch was modified using polyethylene oxide, Pluronic-F127, calcium, increased thickness or polyphosphate, and t...

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Bibliographic Details
Main Authors: Ahad Sabab, Sha Liu, Shari Javadiyan, C. John McAdam, Lyall R. Hanton, Alistair Jukes, Sarah Vreugde, Peter-John Wormald
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97781-8