Osthole improves collagen-induced arthritis in a rat model through inhibiting inflammation and cellular stress

Osthole improves collagen-induced arthritis in a rat model through inhibiting inflammation and cellular stress

Abstract Background Osthole is a natural product that has multiple bioactive functions and has been reported to exert potent immunosuppressive effects. However, the therapeutic effect of osthole on arthritis has not been explored. In the present study, a collagen-induced arthritis rat model, IL-1β-s...

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Bibliographic Details
Main Authors: Renguo Xu, Zhen Liu, Jiande Hou, Tao Huang, Ming Yang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
Osthole
Collagen-induced arthritis
Synovial fibroblasts
Inflammation
NF-κB
Online Access:http://link.springer.com/article/10.1186/s11658-018-0086-0

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