The Epigenomics of Embryonic Pathway Signaling in Colorectal Cancer

Colorectal cancer (CRC) is the second-leading cause of cancer death in developed countries. While early detection (e.g., colonoscopy) generally yields excellent outcomes, metastatic and drug-resistant disease is uniformly fatal, and non-compliance for screening remains over 25%. Familial CRCs (10% o...

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Bibliographic Details
Main Authors: Curt Balch, Jayaram B. Ramapuram, Amit K. Tiwari
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00267/full