Inflammatory cytokine production in tumor cells upon chemotherapy drug exposure or upon selection for drug resistance.
Tumor Necrosis Factor alpha (TNF-α) has been shown to be released by tumor cells in response to docetaxel, and lipopolysaccharides (LPS), the latter through activation of toll-like receptor 4 (TLR4). However, it is unclear whether the former involves TLR4 receptor activation through direct binding o...
Main Authors: | Derek W Edwardson, Justin Boudreau, Jonathan Mapletoft, Carita Lanner, A Thomas Kovala, Amadeo M Parissenti |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5600395?pdf=render |
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