Effectiveness of adjuvant trastuzumab in daily clinical practice

Background. Human epidermal growth factor receptor 2 (HER2) positive breast cancer is an entity with aggressive behaviour. One year of adjuvant trastuzumab significantly improves the disease free survival in the range of 40-50% and reduces the risk of dying from HER2 positive breast cancer by one th...

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Bibliographic Details
Main Authors: Matos Erika, Zakotnik Branko, Kuhar Cvetka Grasic
Format: Article
Language:English
Published: Sciendo 2014-12-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2013-0081
Description
Summary:Background. Human epidermal growth factor receptor 2 (HER2) positive breast cancer is an entity with aggressive behaviour. One year of adjuvant trastuzumab significantly improves the disease free survival in the range of 40-50% and reduces the risk of dying from HER2 positive breast cancer by one third. Adjuvant treatment with trastuzumab became available in Slovenia in 2005 and the aim of this study is to explore, if the exceptional results reported in adjuvant clinical trials are achieved also in daily clinical practice.
ISSN:1581-3207