Suppression of MicroRNA-383 Enhances Therapeutic Potential of Human Bone-Marrow-Derived Mesenchymal Stem Cells in Treating Spinal Cord Injury via GDNF

Suppression of MicroRNA-383 Enhances Therapeutic Potential of Human Bone-Marrow-Derived Mesenchymal Stem Cells in Treating Spinal Cord Injury via GDNF

Background/Aims: Transplantation of bone-marrow-derived mesenchymal stem cells (MSCs) has been used to treat spinal cord injury (SCI) to enhance tissue repair and neural cell regeneration. Glial cell line derived neurotrophic factor (GDNF) is an identified neural growth and survival factor. Here, we...

Full description

Bibliographic Details
Main Authors: Guo-Jun Wei, Gang An, Zuo-Wei Shi, Kai-Fu Wang, Ying Guan, Yan-Song Wang, Bo Han, En-Ming Yu, Peng-Fei Li, Da-Ming Dong, Li-ping Wang, Zhao-wei Teng, De-lai Zhao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Glial cell line derived neurotrophic factor (GDNF)
Mesenchymal stem cells (MSCs)
miR-383
Spinal cord injury (SCI)
Online Access:http://www.karger.com/Article/FullText/468057

Internet

http://www.karger.com/Article/FullText/468057

Similar Items