Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

Constitutive activation of NF-κB is associated with proinflammatory diseases and suppression of the NF-κB signaling pathway has been considered as an effective therapeutic strategy in the treatment of various cancers including hepatocellular carcinoma (HCC). Herein, we report the synthesis of 1,2 ox...

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Bibliographic Details
Main Authors: Chaithanya Somu, Chakrabhavi Dhananjaya Mohan, Sachin Ambekar, Dukanya, Shobith Rangappa, CP Baburajeev, Alexey Sukhorukov, Srishti Mishra, Muthu K Shanmugam, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Basappa, Kanchugarakoppal S. Rangappa
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biotechnology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X19307295

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http://www.sciencedirect.com/science/article/pii/S2215017X19307295

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