Adaption of the ex vivo mycobacterial growth inhibition assay for use with murine lung cells
Abstract In the absence of a correlate(s) of protection against human tuberculosis and a validated animal model of the disease, tools to facilitate vaccine development must be identified. We present an optimised ex vivo mycobacterial growth inhibition assay (MGIA) to assess the ability of host cells...
Main Authors: | Hannah Painter, Satria A. Prabowo, Felipe Cia, Lisa Stockdale, Rachel Tanner, Samuel Willcocks, Rajko Reljic, Helen A. Fletcher, Andrea Zelmer |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-60223-y |
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