Identification and validation of methylation-driven genes prognostic signature for recurrence of laryngeal squamous cell carcinoma by integrated bioinformatics analysis

Identification and validation of methylation-driven genes prognostic signature for recurrence of laryngeal squamous cell carcinoma by integrated bioinformatics analysis

Abstract Background Recurrence remains a major obstacle to long-term survival of laryngeal squamous cell carcinoma (LSCC). We conducted a genome-wide integrated analysis of methylation and the transcriptome to establish methylation-driven genes prognostic signature (MDGPS) to precisely predict recur...

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Bibliographic Details
Main Authors: Jie Cui, Liping Wang, Waisheng Zhong, Zhen Chen, Jie Chen, Hong Yang, Genglong Liu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cancer Cell International
Subjects:
Laryngeal squamous cell carcinoma
DNA methylation-driven genes
Epigenetics
Prediction
Recurrence-free survival
Online Access:http://link.springer.com/article/10.1186/s12935-020-01567-3

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http://link.springer.com/article/10.1186/s12935-020-01567-3

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