Gamma-linolenic acid ameliorates Aβ-induced neuroinflammation through NF-κB and MAPK signalling pathways

Beta-amyloid (Aβ) are known to form senile plaques causing neuroinflammation, which was accepted as the major pathological mechanism in Alzheimer’s disease (AD). To elucidate the molecular mechanism of gamma-linolenic acid (GLA) on neuroprotective actions in inflammation, the effect of GLA on Aβ25–3...

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Bibliographic Details
Main Authors: Kumju Youn, Seonah Lee, Mira Jun
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617307995