A multi-parametric analysis of Trypanosoma cruzi infection: common pathophysiologic patterns beyond extreme heterogeneity of host responses

Abstract The extreme genetic diversity of the protozoan Trypanosoma cruzi has been proposed to be associated with the clinical outcomes of the disease it provokes: Chagas disease (CD). To address this question, we analysed the similarities and differences in the CD pathophysiogenesis caused by diffe...

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Bibliographic Details
Main Authors: Julien Santi-Rocca, Fernando Fernandez-Cortes, Carlos Chillón-Marinas, María-Luisa González-Rubio, David Martin, Núria Gironès, Manuel Fresno
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08086-8