An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis.

RNA structures present throughout RNA virus genomes serve as scaffolds to organize multiple factors involved in the initiation of RNA synthesis. Several of these RNA elements play multiple roles in the RNA replication pathway. An RNA structure formed around the 5'- end of the poliovirus genomic...

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Bibliographic Details
Main Authors: Dorothee A Vogt, Raul Andino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2880563?pdf=render