Generation and validation of novel adeno-associated viral vectors for the analysis of Ca2+ homeostasis in motor neurons
Abstract A finely tuned Ca2+ homeostasis in restricted cell domains is of fundamental importance for neurons, where transient Ca2+ oscillations direct the proper coordination of electro-chemical signals and overall neuronal metabolism. Once such a precise regulation is unbalanced, however, neuronal...
Main Authors: | Rosa Pia Norante, Maria Lina Massimino, Paolo Lorenzon, Agnese De Mario, Caterina Peggion, Mattia Vicario, Mattia Albiero, Maria Catia Sorgato, Raffaele Lopreiato, Alessandro Bertoli |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-06919-0 |
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