Generation and validation of novel adeno-associated viral vectors for the analysis of Ca2+ homeostasis in motor neurons

Abstract A finely tuned Ca2+ homeostasis in restricted cell domains is of fundamental importance for neurons, where transient Ca2+ oscillations direct the proper coordination of electro-chemical signals and overall neuronal metabolism. Once such a precise regulation is unbalanced, however, neuronal...

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Bibliographic Details
Main Authors: Rosa Pia Norante, Maria Lina Massimino, Paolo Lorenzon, Agnese De Mario, Caterina Peggion, Mattia Vicario, Mattia Albiero, Maria Catia Sorgato, Raffaele Lopreiato, Alessandro Bertoli
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06919-0