Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons
Precise coordination of synaptic connections ensures proper information flow within circuits. The activity of presynaptic organizing molecules signaling to downstream pathways is essential for such coordination, though such entities remain incompletely known. We show that LRP4, a conserved transmemb...
Main Authors: | Timothy J Mosca, David J Luginbuhl, Irving E Wang, Liqun Luo |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-06-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/27347 |
Similar Items
-
Postsynaptic Neuroligin-1 Mediates Presynaptic Endocytosis During Neuronal Activity
by: Jiaqi Keith Luo, et al.
Published: (2021-10-01) -
On the Role of Glutamate in Presynaptic Development: Possible Contributions of Presynaptic NMDA Receptors
by: Karlie N. Fedder, et al.
Published: (2015-12-01) -
Presynaptic NMDARs cooperate with local spikes toward GABA release from the reciprocal olfactory bulb granule cell spine
by: Vanessa Lage-Rupprecht, et al.
Published: (2020-11-01) -
NMDA receptor-dependent presynaptic inhibition at the calyx of Held synapse of rat pups
by: Tomoko Oshima-Takago, et al.
Published: (2017-01-01) -
Deletion of LRP1 From Astrocytes Modifies Neuronal Network Activity in an in vitro Model of the Tripartite Synapse
by: Ramona Romeo, et al.
Published: (2021-01-01)