Acute and repeated dose 26-week oral toxicity study of 20(S)-ginsenoside Rg3 in Kunming mice and Sprague–Dawley rats

Acute and repeated dose 26-week oral toxicity study of 20(S)-ginsenoside Rg3 in Kunming mice and Sprague–Dawley rats

Background: 20(S)-ginsenoside-Rg3 (C42H72O13), a natural triterpenoid saponin, is extracted from red ginseng. The increasing use of 20(S)-ginsenoside Rg3 has raised product safety concerns. Methods: In acute toxicity, 20(S)-ginsenoside Rg3 was singly and orally administrated to Kunming mice and Spra...

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Main Authors: Chunmei Li, Zhezhe Wang, Guisheng Li, Zhenhua Wang, Jianrong Yang, Yanshen Li, Hongtao Wang, Haizhu Jin, Junhua Qiao, Hongbo Wang, Jingwei Tian, Albert W. Lee, Yonglin Gao
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Ginseng Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845318301313

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