Downregulation of Candidate Gene Expression and Neuroprotection by Piperine in Streptozotocin-Induced Hyperglycemia and Memory Impairment in Rats

Downregulation of Candidate Gene Expression and Neuroprotection by Piperine in Streptozotocin-Induced Hyperglycemia and Memory Impairment in Rats

There is accumulating evidence showing that hyperglycemia conditions like diabetes possess a greater risk of impairment to the neuronal system because high glucose levels exacerbate oxidative stress, accumulation of amyloid-beta peptides, and mitochondrial dysfunction, and impair cognitive functions...

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Bibliographic Details
Main Authors: Suresh Kumar, Suman Chowdhury, Ajay Razdan, Deepa Kumari, Ram Singh Purty, Heera Ram, Pramod Kumar, Prasunpriya Nayak, Sunil Dutt Shukla
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
neuroprotection
gene expression
hyperglycemia
piperine
Alzheimer’s
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.595471/full

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