Clinical Importance of Placental Testing among Suspected Cases of Congenital Zika Syndrome

Clinical Importance of Placental Testing among Suspected Cases of Congenital Zika Syndrome

Contemporaneous Zika virus (ZIKV) strains can cause congenital Zika syndrome (CZS). Current ZIKV clinical laboratory testing strategies are limited and include IgM serology (which may wane 12 weeks after initial exposure) and nucleic acid testing (NAT) of maternal serum, urine, and placenta for (+)...

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Bibliographic Details
Main Authors: Maxim D. Seferovic, Michelle Turley, Gregory C. Valentine, Martha Rac, Eumenia C. C. Castro, Angela M. Major, Brianna Sanchez, Catherine Eppes, Magdalena Sanz-Cortes, James Dunn, Tiffany F. Kautz, James Versalovic, Kenneth L. Muldrew, Timothy Stout, Michael A. Belfort, Gail Demmler-Harrison, Kjersti M. Aagaard
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
arbovirus
Zika virus
congenital Zika syndrome
placental Zika infection
microcephaly
congenital brain malformations
molecular virology
viral pathogenicity
placental testing
Online Access:https://www.mdpi.com/1422-0067/20/3/712

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https://www.mdpi.com/1422-0067/20/3/712

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