Fighting against Skin Aging

Fighting against Skin Aging

As the most voluminous organ of the body that is exposed to the outer environment, the skin suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance. This aging process is accompanied...

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Main Authors: Shoubing Zhang, Enkui Duan
Format: Article
Language:English
Published: SAGE Publishing 2018-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689717725755
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spelling doaj-8e16da44002444ebbc5e64af63639d8d2020-11-25T03:17:12ZengSAGE PublishingCell Transplantation0963-68971555-38922018-05-012710.1177/0963689717725755Fighting against Skin AgingShoubing Zhang0Enkui Duan1 Central laboratory of Molecular and Cellular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China State Key Lab of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, ChinaAs the most voluminous organ of the body that is exposed to the outer environment, the skin suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance. This aging process is accompanied with phenotypic changes in cutaneous cells as well as structural and functional changes in extracellular matrix components such as collagens and elastin. In this review, we summarize these changes in skin aging, research advances of the molecular mechanisms leading to these changes, and the treatment strategies aimed at preventing or reversing skin aging.https://doi.org/10.1177/0963689717725755
collection DOAJ
language English
format Article
sources DOAJ
author Shoubing Zhang
Enkui Duan
spellingShingle Shoubing Zhang
Enkui Duan
Fighting against Skin Aging
Cell Transplantation
author_facet Shoubing Zhang
Enkui Duan
author_sort Shoubing Zhang
title Fighting against Skin Aging
title_short Fighting against Skin Aging
title_full Fighting against Skin Aging
title_fullStr Fighting against Skin Aging
title_full_unstemmed Fighting against Skin Aging
title_sort fighting against skin aging
publisher SAGE Publishing
series Cell Transplantation
issn 0963-6897
1555-3892
publishDate 2018-05-01
description As the most voluminous organ of the body that is exposed to the outer environment, the skin suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance. This aging process is accompanied with phenotypic changes in cutaneous cells as well as structural and functional changes in extracellular matrix components such as collagens and elastin. In this review, we summarize these changes in skin aging, research advances of the molecular mechanisms leading to these changes, and the treatment strategies aimed at preventing or reversing skin aging.
url https://doi.org/10.1177/0963689717725755
work_keys_str_mv AT shoubingzhang fightingagainstskinaging
AT enkuiduan fightingagainstskinaging
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