The evolution of and challenges in defining the clinical endpoint in tuberculosis treatment trials with non-inferiority designs

The evolution of and challenges in defining the clinical endpoint in tuberculosis treatment trials with non-inferiority designs

Bibliographic Details
Main Authors:	Phillips Patrick PJ, Crook Angela, Nunn Andrew J
Format:	Article
Language:	English
Published:	BMC 2011-12-01
Series:	Trials

Similar Items

An evaluation of culture results during treatment for tuberculosis as surrogate endpoints for treatment failure and relapse.
by: Patrick P J Phillips, et al.
Published: (2013-01-01)

Defining Surrogate Endpoints for Clinical Trials in Severe Falciparum Malaria.
by: Atthanee Jeeyapant, et al.
Published: (2017-01-01)

Defining information fractions in group sequential clinical trials with multiple endpoints
by: Tu Xu, et al.
Published: (2018-06-01)

Statistical Design for Three-Arm Bioequivalence and Non-Inferiority Confirmatory Clinical Trials Using Binary Outcome as Primary Endpoint
by: Chia-Yun Wang, et al.
Published: (2019)

Implications of missing data in tuberculosis non-inferiority clinical trials
by: Rehal, Sunita
Published: (2018)

Exploring Novel Endpoints for Clinical Trials in Kidney Disease: Challenges and Opportunities
by: Prabir Roy-Chaudhury
Published: (2017-05-01)

A systematic review of endpoint definitions in late phase pulmonary tuberculosis therapeutic trials
by: N. K. Hills, et al.
Published: (2021-08-01)

The analysis of multiple endpoints in clinical trials
by: James, Susan Elizabeth
Published: (1993)

Clinical Trial Risk in Non-Hodgkin’s Lymphoma: Endpoint and Target Selection
by: Jayson Lee Parker, et al.
Published: (2011-06-01)

Challenges and Controversies in Defining Totally Drug-Resistant Tuberculosis
by: Peter Cegielski, et al.
Published: (2012-11-01)

Understanding the Use of Composite Endpoints in Clinical Trials
by: C. Eric McCoy
Published: (2018-06-01)

Informative noncompliance in endpoint trials
by: Iglewicz Boris, et al.
Published: (2004-07-01)

Challenges of defining a non-inferiority margin: a case study of non-inferiority randomized controlled trials of oral anti-thrombolytic agents for prophylaxis of venous thromboembolic events after orthopedic surgery
by: Wangge Grace, et al.
Published: (2011-12-01)

Statistical considerations in the design and analysis of non-inferiority trials with binary endpoints in the presence of non-adherence: a simulation study [version 2; peer review: 2 approved]
by: Yin Mo, et al.
Published: (2020-04-01)

Significance of biomarkers and surrogate endpoints in preclinical and clinical trials
by: Ilić Katarina, et al.
Published: (2007-01-01)

Evaluation of the True Endpoint of Clinical Trials for Cancer Cachexia
by: Tateaki Naito
Published: (2019-01-01)

Patients’ preferences for selection of endpoints in cardiovascular clinical trials
by: Robert D. Chow, et al.
Published: (2014-02-01)

Evaluating multiple endpoints in heart failure clinical trials
by: Yang, Yijun
Published: (2016)

The ethics of switch/simplify in antiretroviral trials: non-inferior or just inferior?
by: Andrew Carr, et al.
Published: (2012-01-01)

Seamless superiority/non-inferiority clinical trials
by: Gurary, Ellen
Published: (2019)

Trial design and analysis of endpoints in HIV vaccine trials
by: Richert, Laura
Published: (2013)

Discrepancies in endpoints between clinical trial protocols and clinical trial registration in randomized trials in oncology
by: Victoria J. Serpas, et al.
Published: (2018-12-01)

Upper Limb Evaluation in Duchenne Muscular Dystrophy: Fat-Water Quantification by MRI, Muscle Force and Function Define Endpoints for Clinical Trials.
by: Valeria Ricotti, et al.
Published: (2016-01-01)

Equivalence and non inferiority trials
by: D’Agostino Ralph B
Published: (2011-12-01)

Composite endpoints in COPD: clinically important deterioration in the UPLIFT trial
by: Klaus F. Rabe, et al.
Published: (2020-07-01)

Clinical Trial Design, Endpoints and Regulatory Considerations in Heart Failure
by: Giuseppe MC Rosano
Published: (2019-01-01)

Choosing primary endpoints for clinical trials of health care interventions
by: Charlie McLeod, et al.
Published: (2019-12-01)

Guideline Recommendation for Endpoints Used in Clinical Trials for Functional Dyspepsia
by: Han Hee Lee, et al.
Published: (2018-10-01)

Development of standard clinical endpoints for use in dengue interventional trials.
by: Kay M Tomashek, et al.
Published: (2018-10-01)

Nonparametric statistical procedures for therapeutic clinical trials with survival endpoints
by: Luo, Yingchun
Published: (2007)

Optimising selection of the primary endpoint for acute stroke clinical trials
by: Young, Fiona Beveridge
Published: (2004)

When do we need clinical endpoint adjudication in clinical trials?
by: Claes Held
Published: (2019-01-01)

Evaluating "superiority", "equivalence" and "non-inferiority" in clinical trials
by: Turan Fatma, et al.
Published: (2007-01-01)

A multicenter evaluation of diagnostic tools to define endpoints for programs to eliminate bancroftian filariasis.
by: Katherine Gass, et al.
Published: (2012-01-01)

Evaluation of six months sputum culture conversion as a surrogate endpoint in a multidrug resistant-tuberculosis trial.
by: Paul Meyvisch, et al.
Published: (2018-01-01)

Subjective endpoints in clinical trials: the case for blinded independent central review
by: Walovitch R, et al.
Published: (2013-09-01)

Analysis and design of randomised clinical trials involving competing risks endpoints
by: Wee Joseph, et al.
Published: (2011-05-01)

Clinical Trial Risk in Hepatitis C: Endpoint Selection and Drug Action
by: Nicole A. Tillie, et al.
Published: (2016-01-01)

An Alternative Phase II/III Design in Clinical Trials for Continuous Endpoint
by: Liu, Chia-Pei, et al.
Published: (2010)

Composite neurocognitive endpoints in Alzheimer's disease clinical trials: A commentary
by: Christopher Randolph
Published: (2020-01-01)