TGFBI Protein Is Increased in the Urine of Patients with High-Grade Urothelial Carcinomas, and Promotes Cell Proliferation and Migration
Here, we discovered TGFBI as a new urinary biomarker for muscle invasive and high-grade urothelial carcinoma (UC). After biomarker identification using antibody arrays, results were verified in urine samples from a study population consisting of 303 patients with UC, and 128 urological and 58 popula...
Main Authors: | Kerstin Lang, Selcan Kahveci, Nadine Bonberg, Katharina Wichert, Thomas Behrens, Jan Hovanec, Florian Roghmann, Joachim Noldus, Yu Chun Tam, Andrea Tannapfel, Heiko U. Käfferlein, Thomas Brüning |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/18/4483 |
Similar Items
-
In-Vitro Identification and In-Vivo Confirmation of DNA Methylation Biomarkers for Urothelial Cancer
by: Christina U. Köhler, et al.
Published: (2020-07-01) -
The role of TGFBI in mesothelioma and breast cancer: association with tumor suppression
by: Li Bingyan, et al.
Published: (2012-06-01) -
Lithium chloride promotes the proliferation and autophagy of corneal stromal fibroblasts by TGFBI
by: Dan-Yao Nie, et al.
Published: (2019-11-01) -
Dissecting the Roles of Periostin and TGFBI in Cardiovascular Disease
by: Schwanekamp, Jennifer A.
Published: (2017) -
Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer
by: Sònia Palomeras, et al.
Published: (2019-07-01)