Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation

Candida albicans remains the main etiologic agent of candidiasis, the most common fungal infection and now the third most frequent infection in U.S. hospitals. The scarcity of antifungal agents and their limited efficacy contribute to the unacceptably high morbidity and mortality rates associated wi...

Full description

Bibliographic Details
Main Authors: Jesus A. Romo, Christopher G. Pierce, Ashok K. Chaturvedi, Anna L. Lazzell, Stanton F. McHardy, Stephen P. Saville, Jose L. Lopez-Ribot, Joseph Heitman
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e01991-17