Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
Cryptic translation of the 'non-coding' genome is increasingly recognised, however its biological significance remains unclear. Laumont et al.employ proteogenomic techniques to map the human immunoproteome, and find that approximately 10% of MHC class I-associated peptides are cryptic.
Bibliographic Details
| Main Authors: |
Céline M. Laumont,
Tariq Daouda,
Jean-Philippe Laverdure,
Éric Bonneil,
Olivier Caron-Lizotte,
Marie-Pierre Hardy,
Diana P. Granados,
Chantal Durette,
Sébastien Lemieux,
Pierre Thibault,
Claude Perreault |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2016-01-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms10238
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