Thymosin alpha-1 blocks the accumulation of myeloid suppressor cells in NSCLC by inhibiting VEGF production

Thymosin alpha-1 blocks the accumulation of myeloid suppressor cells in NSCLC by inhibiting VEGF production

Background: Thymosin alpha-1 (TA) has been reported to inhibit tumor growth as an immunomodulator. However, its mechanism of action in immunosuppressive cells is unclear. The purpose of this study was to investigate whether TA can reshape the immune microenvironment by inhibiting the function of mye...

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Bibliographic Details
Main Authors: Zhenzhen Yang, Jiacheng Guo, Kang Cui, Yabing Du, Huan Zhao, Lili Zhu, Lanling Weng, Wenxue Tang, Jiancheng Guo, Tengfei Zhang, Xiaojing Shi, Hong Zong, Shuiling Jin, Wang Ma
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Thymosin alpha-1
Myeloid-derived suppressor cells
Tumor microenvironment
Non-small cell lung carcinoma
VEGF
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220309331

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