Rare Primary Pulmonary Primitive Neuroectodermal Tumor: A Case Report and Literature Review

• Main Authors: Wang N, Dong SS, Wu CL, Wang Y, Meng L, Ren Y, Cui XB, Li M, Qi Y
• Format: Article
• Language: English
• Published: Dove Medical Press 2021-01-01
• Series: OncoTargets and Therapy
• Subjects: primitive neuroectodermal tumor; pulmonary; differential diagnosis
• Online Access: https://www.dovepress.com/rare-primary-pulmonary-primitive-neuroectodermal-tumor-a-case-report-a-peer-reviewed-article-OTT
• ISSN: 1178-6930

Ning Wang,1,* Shuang-Shuang Dong,1,* Chun-Lin Wu,2 Ying Wang,3 Lian Meng,1 Yan Ren,1 Xiao-Bin Cui,1 Man Li,1 Yan Qi1,4 1Department of Pathology, Shihezi University School of Medicine, The First Affiliated Hospital to Shihezi University School of Medicine, Shihezi, Xinjiang 832002, People’s Republic of China; 2Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, Shihezi, Xinjiang 832002, People’s Republic of China; 3Department of Stomatology, Shihezi University School of Medicine, Shihezi, Xinjiang 832002, People’s Republic of China; 4Department of Pathology, Certral People’s Hospital of Zhanjiang & Zhanjiang Central Hospital, Guangdong Medical University, Zhanjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Man LiDepartment of Pathology, Shihezi University School of Medicine & The First Affiliated Hospital to Shihezi University School of Medicine, North 2 Road, Shihezi, 832002 Xinjiang, People’s Republic of ChinaTel [phone]Email [e-mail] QiDepartment of Pathology, Certral People’s Hospital of Zhanjiang & Zhanjiang Central Hospital, Guangdong Medical University, Zhanjiang, People’s Republic of ChinaTel +86 [phone]Email [e-mail]: Primitive neuroectodermal tumors (PNETs) arising from the lung without thoracic wall involvement are extremely rare and particularly aggressive neoplasms. Herein, we present the case of a 41-year-old woman with pulmonary PNET diagnosed following histopathological, immunohistochemical, and molecular pathological examination of a surgical biopsy specimen. The case report is accompanied by a literature review of primary pulmonary PNETs.Keywords: primitive neuroectodermal tumor, pulmonary, differential diagnosis