Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report

Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report

<p class="p p-first-last" id="__p3">Identifying fastidious pathogens in patients with prosthetic joint infection (PJI) by culture is challenging. Metagenomic next-generation sequencing (mNGS) is a novel culture-independent approach that is associated with a higher likelihoo...

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Main Authors: Z. Huang, C. Zhang, W. Li, X. Fang, Q. Wang, L. Xing, Y. Li, X. Nie, B. Yang, W. Zhang
Format: Article
Language:English
Published: Copernicus Publications 2019-01-01
Series:Journal of Bone and Joint Infection
Online Access:https://jbji.copernicus.org/articles/4/50/2019/jbji-4-50-2019.pdf
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spelling doaj-8dfdcb07b1be44efb0605cb0ab907a7c2021-03-03T14:44:10ZengCopernicus PublicationsJournal of Bone and Joint Infection2206-35522019-01-014505510.7150/jbji.30615Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case reportZ. Huang0C. Zhang1W. Li2X. Fang3Q. Wang4L. Xing5Y. Li6X. Nie7B. Yang8W. Zhang9Department of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, ChinaDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, ChinaDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, ChinaDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, ChinaDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, ChinaBGI Genomics, BGI-Shenzhen, Shenzhen 518083, ChinaBGI Genomics, BGI-Shenzhen, Shenzhen 518083, ChinaBGI Genomics, BGI-Shenzhen, Shenzhen 518083, ChinaDepartment of Laboratory Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, ChinaDepartment of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, China<p class="p p-first-last" id="__p3">Identifying fastidious pathogens in patients with prosthetic joint infection (PJI) by culture is challenging. Metagenomic next-generation sequencing (mNGS) is a novel culture-independent approach that is associated with a higher likelihood for identifying pathogens. We present a case where mNGS was implemented to identify <em>Parvimonas micra</em>, a rarely reported and difficult-to-culture PJI pathogen.</p>https://jbji.copernicus.org/articles/4/50/2019/jbji-4-50-2019.pdf
collection DOAJ
language English
format Article
sources DOAJ
author Z. Huang
C. Zhang
W. Li
X. Fang
Q. Wang
L. Xing
Y. Li
X. Nie
B. Yang
W. Zhang
spellingShingle Z. Huang
C. Zhang
W. Li
X. Fang
Q. Wang
L. Xing
Y. Li
X. Nie
B. Yang
W. Zhang
Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report
Journal of Bone and Joint Infection
author_facet Z. Huang
C. Zhang
W. Li
X. Fang
Q. Wang
L. Xing
Y. Li
X. Nie
B. Yang
W. Zhang
author_sort Z. Huang
title Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report
title_short Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report
title_full Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report
title_fullStr Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report
title_full_unstemmed Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report
title_sort metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to parvimonas micra: a case report
publisher Copernicus Publications
series Journal of Bone and Joint Infection
issn 2206-3552
publishDate 2019-01-01
description <p class="p p-first-last" id="__p3">Identifying fastidious pathogens in patients with prosthetic joint infection (PJI) by culture is challenging. Metagenomic next-generation sequencing (mNGS) is a novel culture-independent approach that is associated with a higher likelihood for identifying pathogens. We present a case where mNGS was implemented to identify <em>Parvimonas micra</em>, a rarely reported and difficult-to-culture PJI pathogen.</p>
url https://jbji.copernicus.org/articles/4/50/2019/jbji-4-50-2019.pdf
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