Ototoxicity-induced loss of hearing and inner hair cells is attenuated by HSP70 gene transfer
The most common reason for sensorineural deafness is death of hair cells (HCs). Heat shock proteins (HSPs) are molecular chaperones that participate in folding, targeting, and degrading proteins. HSP expression is increased in response to various environmental stresses to protect cells from damage....
Main Authors: | Yohei Takada, Tomoko Takada, Min Young Lee, Donald L Swiderski, Lisa L Kabara, David F Dolan, Yehoash Raphael |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-01-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050116300316 |
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