Basal ganglia dopamine loss due to defect in purine recycling

Basal ganglia dopamine loss due to defect in purine recycling

Several rare inherited disorders have provided valuable experiments of nature highlighting specific biological processes of particular importance to the survival or function of midbrain dopamine neurons. In both humans and mice, deficiency of hypoxanthine-guanine phosphoribosyl transferase (HPRT) is...

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Bibliographic Details
Main Authors:	Kiyoshi Egami, Silaja Yitta, Suhail Kasim, J. Chris Lewers, Rosalinda C. Roberts, Mohamed Lehar, H.A. Jinnah
Format:	Article
Language:	English
Published:	Elsevier 2007-05-01
Series:	Neurobiology of Disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996107000265

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