Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

Early life stress alters behavioural response to adult stress in female mice. Here authors transcriptionally profile three brain regions involved in reward (ventral tegmental area, nucleus accumbens, and prefrontal cortex) in both male and female adult mice after early life and/or adult stress

Bibliographic Details
Main Authors: Catherine Jensen Peña, Milo Smith, Aarthi Ramakrishnan, Hannah M. Cates, Rosemary C. Bagot, Hope G. Kronman, Bhakti Patel, Austin B. Chang, Immanuel Purushothaman, Joel Dudley, Hirofumi Morishita, Li Shen, Eric J. Nestler
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13085-6
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spelling doaj-8dd8ca4d366347b8963002cc46ccc6112021-05-11T11:55:35ZengNature Publishing GroupNature Communications2041-17232019-11-0110111310.1038/s41467-019-13085-6Early life stress alters transcriptomic patterning across reward circuitry in male and female miceCatherine Jensen Peña0Milo Smith1Aarthi Ramakrishnan2Hannah M. Cates3Rosemary C. Bagot4Hope G. Kronman5Bhakti Patel6Austin B. Chang7Immanuel Purushothaman8Joel Dudley9Hirofumi Morishita10Li Shen11Eric J. Nestler12Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiPrinceton Neuroscience Institute, Princeton UniversityNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount SinaiEarly life stress alters behavioural response to adult stress in female mice. Here authors transcriptionally profile three brain regions involved in reward (ventral tegmental area, nucleus accumbens, and prefrontal cortex) in both male and female adult mice after early life and/or adult stresshttps://doi.org/10.1038/s41467-019-13085-6
collection DOAJ
language English
format Article
sources DOAJ
author Catherine Jensen Peña
Milo Smith
Aarthi Ramakrishnan
Hannah M. Cates
Rosemary C. Bagot
Hope G. Kronman
Bhakti Patel
Austin B. Chang
Immanuel Purushothaman
Joel Dudley
Hirofumi Morishita
Li Shen
Eric J. Nestler
spellingShingle Catherine Jensen Peña
Milo Smith
Aarthi Ramakrishnan
Hannah M. Cates
Rosemary C. Bagot
Hope G. Kronman
Bhakti Patel
Austin B. Chang
Immanuel Purushothaman
Joel Dudley
Hirofumi Morishita
Li Shen
Eric J. Nestler
Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
Nature Communications
author_facet Catherine Jensen Peña
Milo Smith
Aarthi Ramakrishnan
Hannah M. Cates
Rosemary C. Bagot
Hope G. Kronman
Bhakti Patel
Austin B. Chang
Immanuel Purushothaman
Joel Dudley
Hirofumi Morishita
Li Shen
Eric J. Nestler
author_sort Catherine Jensen Peña
title Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
title_short Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
title_full Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
title_fullStr Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
title_full_unstemmed Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
title_sort early life stress alters transcriptomic patterning across reward circuitry in male and female mice
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-11-01
description Early life stress alters behavioural response to adult stress in female mice. Here authors transcriptionally profile three brain regions involved in reward (ventral tegmental area, nucleus accumbens, and prefrontal cortex) in both male and female adult mice after early life and/or adult stress
url https://doi.org/10.1038/s41467-019-13085-6
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