1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?

1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?

Objective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosi...

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Main Authors: M. Szewczyk-Bieda, A. K. Kanodia, G. Main, M. S. Eljamel
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2011/371073
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spelling doaj-8dced47052de4a3eadd3a76f4ff4cebc2020-11-24T23:24:23ZengHindawi LimitedCase Reports in Radiology2090-68622090-68702011-01-01201110.1155/2011/3710733710731H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?M. Szewczyk-Bieda0A. K. Kanodia1G. Main2M. S. Eljamel3Department of Clinical Radiology, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UKDepartment of Clinical Radiology, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UKDepartment of Clinical Radiology, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UKDepartment of Neurosurgery, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UKObjective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosis on MRI. Results. MRS performed using single voxel and chemical shift/multivoxel techniques was within normal limits. A repeat scan 6 months later showed progressive disease, and biopsy was performed that proved the diagnosis of glioblastoma. Conclusion. Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term.http://dx.doi.org/10.1155/2011/371073
collection DOAJ
language English
format Article
sources DOAJ
author M. Szewczyk-Bieda
A. K. Kanodia
G. Main
M. S. Eljamel
spellingShingle M. Szewczyk-Bieda
A. K. Kanodia
G. Main
M. S. Eljamel
1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
Case Reports in Radiology
author_facet M. Szewczyk-Bieda
A. K. Kanodia
G. Main
M. S. Eljamel
author_sort M. Szewczyk-Bieda
title 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
title_short 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
title_full 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
title_fullStr 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
title_full_unstemmed 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
title_sort 1h mr spectroscopy in gliomatosis: is there a sensitivity issue?
publisher Hindawi Limited
series Case Reports in Radiology
issn 2090-6862
2090-6870
publishDate 2011-01-01
description Objective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosis on MRI. Results. MRS performed using single voxel and chemical shift/multivoxel techniques was within normal limits. A repeat scan 6 months later showed progressive disease, and biopsy was performed that proved the diagnosis of glioblastoma. Conclusion. Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term.
url http://dx.doi.org/10.1155/2011/371073
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AT akkanodia 1hmrspectroscopyingliomatosisisthereasensitivityissue
AT gmain 1hmrspectroscopyingliomatosisisthereasensitivityissue
AT mseljamel 1hmrspectroscopyingliomatosisisthereasensitivityissue
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