1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?

Objective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosi...

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Bibliographic Details
Main Authors: M. Szewczyk-Bieda, A. K. Kanodia, G. Main, M. S. Eljamel
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2011/371073
Description
Summary:Objective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosis on MRI. Results. MRS performed using single voxel and chemical shift/multivoxel techniques was within normal limits. A repeat scan 6 months later showed progressive disease, and biopsy was performed that proved the diagnosis of glioblastoma. Conclusion. Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term.
ISSN:2090-6862
2090-6870