Mesenchymal Stem Cell-Secreted Exosome Promotes Chemoresistance in Breast Cancer via Enhancing miR-21-5p-Mediated S100A6 Expression

Mesenchymal Stem Cell-Secreted Exosome Promotes Chemoresistance in Breast Cancer via Enhancing miR-21-5p-Mediated S100A6 Expression

Emerging evidence has shown the role of mesenchymal stem cell-derived exosome (MSC-exo) in inducing resistance of cancer cells to chemotherapy. However, it remains unclear whether the change of MSC-exo in response to chemotherapy also contributes to chemoresistance. In this study, we investigated th...

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Bibliographic Details
Main Authors: Tao Luo, Qiaoyuan Liu, Aihua Tan, Lixia Duan, Yuxian Jia, Li Nong, Jing Tang, Wenxian Zhou, Weimin Xie, Yongkui Lu, Qiang Yu, Yan Liu
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Oncolytics
Subjects:
doxorubicin resistance
mesenchymal stem cell exosome
miR-21-5p
S100A6
breast cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520301595

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http://www.sciencedirect.com/science/article/pii/S2372770520301595

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