circNrxn2 Promoted WAT Browning via Sponging miR-103 to Relieve Its Inhibition of FGF10 in HFD Mice
The accumulation of excess white adipose tissue (WAT) has harmful consequences on metabolic health. WAT browning confers beneficial effects on adiposity, insulin resistance, and hyperlipidemia. In this study, it was found out that circNrxn2 sponged miR-103 and enhanced FGF10 levels in HFD mice WAT....
Main Authors: | Tiantian Zhang, Zhenzhen Zhang, Tianyu Xia, Chenlong Liu, Chao Sun |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-09-01
|
Series: | Molecular Therapy: Nucleic Acids |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253119301830 |
Similar Items
-
Circ_0001367 inhibits glioma proliferation, migration and invasion by sponging miR-431 and thus regulating NRXN3
by: Liang Liu, et al.
Published: (2021-05-01) -
circARF3 Alleviates Mitophagy-Mediated Inflammation by Targeting miR-103/TRAF3 in Mouse Adipose Tissue
by: Zhenzhen Zhang, et al.
Published: (2019-03-01) -
Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models.
by: Liyun Zeng, et al.
Published: (2013-01-01) -
Mutation analysis of the NRXN1 gene in autism spectrum disorders
by: Onay H, et al.
Published: (2016-12-01) -
HFD and HFD-provoked hepatic hypoxia act as reciprocal causation for NAFLD via HIF-independent signaling
by: Xiaofang Zhang, et al.
Published: (2020-11-01)