Modeling systems-level regulation of host immune responses.

Modeling systems-level regulation of host immune responses.

Many pathogens are able to manipulate the signaling pathways responsible for the generation of host immune responses. Here we examine and model a respiratory infection system in which disruption of host immune functions or of bacterial factors changes the dynamics of the infection. We synthesize the...

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Bibliographic Details
Main Authors: Juilee Thakar, Mylisa Pilione, Girish Kirimanjeswara, Eric T Harvill, Réka Albert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1892604?pdf=render

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