THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGE

THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGE

There was studied of protective effects of homologous cellular peptides on corneal graft endothelium cells during the corneal organ culture (24 days) and corneal cold storage (9 days). The dynamic of endothelial cells (EC) ultrastuktural changes during the storage, decrease of endothelial cells dens...

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Main Authors: S.A. Borzenok, O.I. Rolik, N.A. Onischenko, Y.A. Komakh, V.V. Delektorskaya
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2012-03-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
cornea endothelium cells, corneal graft, cytoplasm peptides, regulatory peptides, cornea preservation.
Online Access:https://journal.transpl.ru/vtio/article/view/117
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spelling doaj-8db6c4e6dae3472abe5067e78e8e40462021-07-29T09:08:25ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov Vestnik Transplantologii i Iskusstvennyh Organov1995-11912012-03-01141788510.15825/1995-1191-2012-1-78-8560THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGES.A. Borzenok0O.I. Rolik1N.A. Onischenko2Y.A. Komakh3V.V. Delektorskaya4The Fedorov Eye Microsurgery Federal State Institution, MoscowThe Fedorov Eye Microsurgery Federal State Institution, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowThe Fedorov Eye Microsurgery Federal State Institution, MoscowN.N. Blokhin Russian Cancer Research Center RAMS, MoscowThere was studied of protective effects of homologous cellular peptides on corneal graft endothelium cells during the corneal organ culture (24 days) and corneal cold storage (9 days). The dynamic of endothelial cells (EC) ultrastuktural changes during the storage, decrease of endothelial cells density, percentage of hexagonal-shape cells, average area and electronic microscopy were analised. Tissue-specific regulatory corneal peptides exhibited clear protective effect on ultra structure of grafts’ endothelial cells during the preservation, increase density cell-cell contact, prolong term of organ culture (till 16 days) and cold storage (till 9 days).https://journal.transpl.ru/vtio/article/view/117cornea endothelium cells, corneal graft, cytoplasm peptides, regulatory peptides, cornea preservation.
collection DOAJ
language Russian
format Article
sources DOAJ
author S.A. Borzenok
O.I. Rolik
N.A. Onischenko
Y.A. Komakh
V.V. Delektorskaya
spellingShingle S.A. Borzenok
O.I. Rolik
N.A. Onischenko
Y.A. Komakh
V.V. Delektorskaya
THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGE
Vestnik Transplantologii i Iskusstvennyh Organov
cornea endothelium cells, corneal graft, cytoplasm peptides, regulatory peptides, cornea preservation.
author_facet S.A. Borzenok
O.I. Rolik
N.A. Onischenko
Y.A. Komakh
V.V. Delektorskaya
author_sort S.A. Borzenok
title THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGE
title_short THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGE
title_full THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGE
title_fullStr THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGE
title_full_unstemmed THE USE OF HOMOLOGOUS CELLULAR PEPTIDES DURING MEDIUM-TERM CORNEAL ORGAN CULTURE AND CORNEAL COLD STORAGE
title_sort use of homologous cellular peptides during medium-term corneal organ culture and corneal cold storage
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
series Vestnik Transplantologii i Iskusstvennyh Organov
issn 1995-1191
publishDate 2012-03-01
description There was studied of protective effects of homologous cellular peptides on corneal graft endothelium cells during the corneal organ culture (24 days) and corneal cold storage (9 days). The dynamic of endothelial cells (EC) ultrastuktural changes during the storage, decrease of endothelial cells density, percentage of hexagonal-shape cells, average area and electronic microscopy were analised. Tissue-specific regulatory corneal peptides exhibited clear protective effect on ultra structure of grafts’ endothelial cells during the preservation, increase density cell-cell contact, prolong term of organ culture (till 16 days) and cold storage (till 9 days).
topic cornea endothelium cells, corneal graft, cytoplasm peptides, regulatory peptides, cornea preservation.
url https://journal.transpl.ru/vtio/article/view/117
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